Lipin-1 flexes its muscle in autophagy
                    
                        
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NASA flexes its artificial muscles
When the MUSES-C mission spacecraft reaches the small near-Earth asteroid 4660 Nereus and begins its landing sequence sometime in 2003, it will drop a palm-size nanorover to the surface before touching down. This small NASA vehicle will view the surface with both a visual and an infrared camera. NASA scientists anticipate that, from time to time, dust will accumulate on the viewing window. To f...
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Our lab is focused on the study of a family of proteins known as lipins that exhibit phosphatidic acid phosphatase activity, and the role they play in macrophages. Up to date 5 proteins have been described that are encoded by three different genes. The lpin1 gene may undergo alternative splicing. generating lipin1α, β and γ isoforms. Lipin1γ is present only in humans. These proteins have a very...
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The three lipin phosphatidate phosphatase (PAP) enzymes catalyze a step in glycerolipid biosynthesis, the conversion of phosphatidate to diacylglycerol. Lipin-1 is critical for lipid synthesis and homeostasis in adipose tissue, liver, muscle, and peripheral nerves. Little is known about the physiological role of lipin-2, the predominant lipin protein present in liver and the deficient gene prod...
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A n electric current gives a strange, tingling sensation when it flows into your skin, as if mineral water were bubbling in your forearm. It is odd to see the flat electrode on your skin and not know how strong those pins and needles will become; but the anticipated prickling stays away. It doesn’t take much electricity to get the muscles moving: first the fingers lift, then the heel of the han...
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ژورنال
عنوان ژورنال: Cell Cycle
سال: 2014
ISSN: 1538-4101,1551-4005
DOI: 10.4161/15384101.2014.988105